Quasi-Linear Viscoelastic theory applied to internal shearing of porcine aortic valve leaflets.

摘要: The elements of Quasi-Linear Viscoelastic (QLV) theory have been applied to model the internal shear mechanics fresh and glutaraldehyde-fixed porcine aortic valve leaflets. A novel function estimation method was used extract material functions from experimental data obtained at one strain rate, predict response different rates. In general, experiments predictions were in good agreement, larger discrepancies being prediction peak stresses hysteresis cyclic shear. shear, fixed tissues are stiffer (mean initial modulus, 13 kPa versus 427 Pa), take longer relax steady state τ2 4,736 s 1,764 s) with a slower relaxation rate magnitude G(0), 1 s−1 5 ), lesser extent than percentage stress remaining after relaxation, 60 45 percent). All differences significant p = 0.04 or less, except for slope. We conclude that can complement traditional tensile biaxial toward providing complete mechanical description soft biomaterials, particularly when evaluating alternative chemical fixation techniques.