作者: Alejandro de la Sierra , Josep Redon , José R. Banegas , Julián Segura , Gianfranco Parati
DOI: 10.1161/HYPERTENSIONAHA.108.124008
关键词: Diabetes mellitus 、 Blood pressure 、 Circadian rhythm 、 Cardiology 、 Cohort study 、 Ambulatory blood pressure 、 Obesity 、 Ambulatory 、 Surgery 、 Internal medicine 、 Medicine 、 Risk factor
摘要: Ambulatory blood pressure (BP) monitoring has become useful in the diagnosis and management of hypertensive individuals. In addition to 24-hour values, circadian variation BP adds prognostic significance predicting cardiovascular outcome. However, magnitude patterns large studies hardly been noticed. Our aims were determine prevalence assess clinical conditions associated with nondipping status groups both treated untreated subjects, studied separately. Clinical data ambulatory obtained from 42,947 patients included Spanish Society Hypertension Blood Pressure Monitoring Registry. They 8384 previously 34,563 hypertensives. Twenty-four-hour was performed an oscillometric device (SpaceLabs 90207). A pattern defined when nocturnal systolic dip <10% daytime BP. The 41% group 53% patients. groups, advanced age, obesity, diabetes mellitus, overt or renal disease a blunted decline (P<0.001). patients, use higher number antihypertensive drugs but not time day at which administered. conclusion, (the pattern) is common high risk nondipping, suggesting that may be merely marker risk.