Computational Field Shaping for Deep Brain Stimulation With Thousands of Contacts in a Novel Electrode Geometry.

摘要: Objective Deep brain stimulation (DBS) alleviates symptoms associated with some neurological disorders by stimulating specific deep targets. However, incomplete of the target region can provide suboptimal therapy, and spread to tissue outside generate side-effects. Existing DBS electrodes profiles that are roughly spherical, neither matching nor enabling mapping therapeutic We present a novel electrode design will perform computational modeling new investigate its use as next generation electrode. Materials Methods Computational simulations finite element model performed for both commercially available electrode. Results Computational results show this is able steer radially around device, creating voltage distributions may more closely match targets. Conclusion The ability better anatomy compensate targeting errors during implantation enable strict localization generated fields within tissues, potentially providing complete symptom alleviation while reducing occurrence