The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

作者: Holly K. Bryan , Adedamola Olayanju , Christopher E. Goldring , B. Kevin Park

DOI: 10.1016/J.BCP.2012.11.016

关键词: Protein kinase BBiochemistryPhosphorylationKEAP1BiologyKinaseCellular homeostasisTranscription factorPI3K/AKT/mTOR pathwayEpigenetics

摘要: … with Cys151, this cysteine may undergo S-nitrosylation facilitated by its flanking residues (K131, R135, K150) [70] and this idea of S-nitrosylation of Keap1 is supported by others [71], [72…

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