The short-term impact of the catheter ablation on noninvasive autonomic nervous system parameters in patients with paroxysmal atrial fibrillation.

摘要: Background The autonomic nervous system (ANS) is a potentially potent modulator of the initiation and perpetuation atrial fibrillation (AF), whereas presence AF can activate alter ANS. catheter ablation (AFCA) may cause cardiac ANS dysfunction, restoration sinus rhythm or sympathovagal imbalance by AFCA reverse this process. Our principal goal was to investigate short-term effect on functions evaluated noninvasive chronotropic (CI), resting heart rate (RHR), recovery (HRR) indices. Method A total 45 patients were enrolled with symptomatic, drug refractory paroxysmal undergoing first cryoballoon (CB) pulmonary vein antrum isolation (PVAI) one 28-mm CB using single 3-minute freeze techniques without bonus applications. All underwent symptom-limited exercise treadmill testing evaluate parameters before PVAI. For those who remained in rhythm, an additional test repeated after 1 3 months discharge. Results CI RHR/HRR indices impaired PVAI persisted post-PVAI months. However, these not different recurrence. Conclusion This study demonstrated that successful might concurrently impair parameters. between sympathetic parasympathetic activity could either become antiarrhythmic and/or proarrhythmic based which two components going prevail AFCA. balance also be another hypothetical mechanism for recurrence particularly absence PV reconnection.