Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells
作者： C. C. Ong , A. M. Jubb , P. M. Haverty , W. Zhou , V. Tran
关键词: Cancer research 、 Cell cycle 、 Biology 、 Kinase 、 Actin cytoskeleton organization 、 Inhibitor of apoptosis 、 Carcinogenesis 、 PAK1 、 p21-activated kinases 、 Growth factor receptor 、 Cell biology
摘要: p21-activated kinases (PAKs) are serine/threonine protein kinases that serve as important mediators of Rac and Cdc42 GTPase function as well as pathways required for Ras-driven …
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