Evaluating TBK1 as a Therapeutic Target in Cancers with Activated IRF3
作者： Asli Muvaffak , Qi Pan , Haiyan Yan , Rafael Fernandez , Jongwon Lim
DOI: 10.1158/1541-7786.MCR-13-0642
关键词: KRAS 、 Cancer 、 Synthetic lethality 、 Cancer cell 、 Cell growth 、 Low protein 、 Biology 、 Kinase 、 Cancer research 、 Protein kinase A
摘要: … Here, the effect of TBK1 on proliferation in a panel of cancer … of TBK1 activity by knockdown or treatment with TBK1 inhibitors did … of phosphorylated S172 of TBK1 (pTBK1 S172 ). Finally, …
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