Trends in acute reperfusion therapy for ST-segment elevation myocardial infarction from 1999 to 2006: we are getting better but we have got a long way to go.

作者: K. A. Eagle , B. K. Nallamothu , R. H. Mehta , C. B. Granger , P. G. Steg

DOI: 10.1093/EURHEARTJ/EHN069

关键词: MedicineST elevationConventional PCIPercutaneous coronary interventionMyocardial infarctionReperfusion therapyST segmentCardiologyElectrocardiographyInternal medicineCoronary artery bypass surgery

摘要: Aim Many patients who are eligible for acute reperfusion therapy receive it after substantial delays or not at all. We wanted to determine whether over the years more receiving therapy. Methods and results This analysis is based on 10 954 with ST elevation left bundle-branch block presenting within 12 h of symptom onset enrolled in GRACE registry between April 1999 June 2006. Over this time, there was an increasing trend use primary percutaneous coronary intervention (PCI) from 15% 44% ( P 30 min 42% those undergoing PCI had door-to-balloon times >90 min. Conclusion Primary now used much than fibrinolysis. Although hospital mortality fibrinolytic have improved, 40% reperfused still outside time window recommended, one-third potentially no reperfusion.

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