Randomized Trial of Diet and Gastroplasty Compared with Diet Alone in Morbid Obesity

作者: Teis Andersen , Ole G. Backer , Knud H. Stokholm , Flemming Quaade

DOI: 10.1056/NEJM198402093100604

关键词: SurgeryMedicineWeight lossGastroenterologyMedian bodyRandomized controlled trialInternal medicineObesityMorbid obesityMorbidly obeseIn patientStomach surgeryGeneral Medicine

摘要: We compared the weight-reducing effect of diet and gastroplasty with that alone in a randomized trial 60 morbidly obese patients followed for two years. Initial median body weight was 120 kg randomly assigned to plus 115 those alone. Maximum losses did not differ significantly between groups (26.1 group 22.0 treated alone, P greater than 0.05). The risk Type II error true difference larger 9.5 less 5 per cent. However, regained more after maximum loss had been achieved, so favorable net outcome at years (P

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