Glandular epithelial induction by embryonic mesenchyme in adult bladder epithelium of BALB/c mice.

摘要: Tissue recombinants prepared with epithelium of the urinary bladder adult mice and mesenchyme embryonic urogenital sinus were grown as renal capsular grafts in male hosts. Under these conditions epithelium, which is derived embryologically from sinus, was induced to form prostate-like acini. The relevance this observation McNeal's (1978) hypothesis, that formation prostatic acini during development human benign hyperplasia may be a reexpression inductive capacity stroma, discussed.