ANTIOXIDANT STATUS AND ALCOHOL-RELATED DISEASES

摘要: Chronic ethanol consumption is associated with increased incidence of a variety illnesses, including cancer Studies have shown that may result in oxidative stress formation lipid peroxides and free radicals. The susceptibility given tissue to peroxidation is, however, function the overall balance between prooxidants antioxidant defence systems. latter involve both intracellular extracellular protective factors were nutrients play an important role. Impaired nutritional status different vitamins trace elements been reported alcoholics. Reduced levels vitamin E found serum alcoholics without liver disease biopsies from cirrhosis. These findings be due as experimental animals, importance since major, if not only, hpid-soluble radical scavenger some tissues. capacity has several tissues promote generation radicals which damage cells directly, induce inflammation accelerate collagen synthesis. events progress disease. initiation promotion presently great interest. role alcohol-related remains unresolved. Further research required establish these reactive species pathogenesis disease, evaluate nutrition favour mechanisms.