Structure and in vivo function of Hsp90

作者: Laurence H Pearl , Chrisostomos Prodromou

DOI: 10.1016/S0959-440X(99)00047-0

关键词: Protein foldingStructural biologyIn vivoSignal transductionCo-chaperoneHsp90Plasma protein bindingCell biologyBiologyChaperone (protein)Computational biology

摘要: … Hsp90-based chaperone system. We also review progress in defining the client range of Hsp90 … emergence of Hsp90 as a target for the structure-aided design of new anticancer drugs. …

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