作者: Michael Campoli , Scott Freeman , David G. Brodland , John Zitelli
DOI: 10.1007/978-1-4471-2152-7_18
关键词: Sectioning technique 、 Melanoma 、 Surgery 、 Cutaneous melanoma 、 Micrographic surgery 、 Surgical excision 、 Malignancy 、 Dermatology 、 Surgical margin 、 Frozen section procedure 、 Medicine
摘要: Melanoma is a clinically and biologically diverse malignancy for which complete surgical excision offers the only chance cure. Current guidelines margins are based on consensus recommendations, clear, evidence-based data to guide surgeon in each case limited. Mohs micrographic surgery (MMS) ability assess 100% of margin, far better than evaluated with standard bread-loaf sectioning technique. Immunohistochemical stains such as MART-1 allow reliable identification melanoma frozen sections produce cure rates at least good traditional margins.