Root coverage of multiple gingival recessions treated with coronally advanced flap associated with xenogeneic acellular dermal matrix or connective tissue graft: a 6-month split-mouth controlled and randomized clinical trial.

作者: Mabelle Freitas Monteiro , Daiane Cristina Peruzzo , Julio Cesar Joly , Renato Maluta

DOI: 10.1007/S00784-021-03879-8

关键词: UrologySignificant differenceConnective tissueRoot coverageDermal matrixGingival recessionRandomized controlled trialMedicine

摘要: This study aimed to compare xenogeneic dermal matrix (XDM) connective tissue graft (CTG) associated with coronally advanced flap (CAF) in treating Miller’s class I and II (RT1) multiple gingival recession a split-mouth randomized clinical trial. Fifteen patients bilateral recessions were selected. The patient’s side receiving each treatment was randomly allocated receive XDM or CTG. parameters measured at baseline 6 months of follow-up. At months, no significant difference the root coverage (RC) (95.28 ± 6.89% for CTG 92.68 7.35% XDM) keratinized (KT) gain (0.91 0.46 mm 0.74 0.39 observed between groups (p > 0.05). group presented higher complete (CRC) than (60% 33%, respectively) = 0.045). Multiple logistic regression indicated that 0.01) KT interaction 0.02) negatively interfered CRC. A 1-mm increase when using increases almost times chance achieving CRC, reached similar CRC probability receptor area least 2 KT. Both treatments effective recession; gain, GR reduction, RC obtained XDM, while promoted XDM. Moreover, amount determinant produces limited sites reduced Brazilian Clinical Trials Registry (REBEC) number RBR-56NZQ6

参考文章(35)
Sofia Aroca, Bálint Molnár, Péter Windisch, István Gera, Giovanni E. Salvi, Dimitris Nikolidakis, Anton Sculean, Treatment of multiple adjacent Miller class I and II gingival recessions with a Modified Coronally Advanced Tunnel (MCAT) technique and a collagen matrix or palatal connective tissue graft: a randomized, controlled clinical trial Journal of Clinical Periodontology. ,vol. 40, pp. 713- 720 ,(2013) , 10.1111/JCPE.12112
G. Zucchelli, M. De Sanctis, Treatment of Multiple Recession-Type Defects in Patients With Esthetic Demands Journal of Periodontology. ,vol. 71, pp. 1506- 1514 ,(2000) , 10.1902/JOP.2000.71.9.1506
Alexandra Stähli, Richard J. Miron, Dieter D. Bosshardt, Anton Sculean, Reinhard Gruber, Collagen Membranes Adsorb the Transforming Growth Factor‐β Receptor I Kinase‐Dependent Activity of Enamel Matrix Derivative Journal of Periodontology. ,vol. 87, pp. 583- 590 ,(2016) , 10.1902/JOP.2016.150538
Lisa Gammel, Friedrich W. Neukam, Karl A. Schlegel, Christian M. Schmitt, Ragai E. Matta, Tobias Moest, Julia Humann, Soft tissue volume alterations after connective tissue grafting at teeth: the subepithelial autologous connective tissue graft versus a porcine collagen matrix - a pre-clinical volumetric analysis. Journal of Clinical Periodontology. ,vol. 43, pp. 609- 617 ,(2016) , 10.1111/JCPE.12547
Pier Francesco Nocini, Roberto Castellani, Guglielmo Zanotti, Federico Gelpi, Ugo Covani, Simone Marconcini, Daniele de Santis, Extensive keratinized tissue augmentation during implant rehabilitation after Le Fort I osteotomy: using a new porcine collagen membrane (Mucoderm). Journal of Craniofacial Surgery. ,vol. 25, pp. 799- 803 ,(2014) , 10.1097/SCS.0000000000000524
Gregory-George Zafiropoulos, Giorgio Deli, Oliver Hoffmann, Gordon John, Changes of the peri-implant soft tissue thickness after grafting with a collagen matrix Journal of Indian Society of Periodontology. ,vol. 20, pp. 441- 445 ,(2016) , 10.4103/0972-124X.181245
Marta Cieślik-Wegemund, Beata Wierucka-Młynarczyk, Marta Tanasiewicz, Łukasz Gilowski, Tunnel Technique With Collagen Matrix Compared With Connective Tissue Graft for Treatment of Periodontal Recession: A Randomized Clinical Trial Journal of Periodontology. ,vol. 87, pp. 1436- 1443 ,(2016) , 10.1902/JOP.2016.150676
Séverine Vincent-Bugnas, Gwenaël Borie, Yves Charbit, Treatment of multiple maxillary adjacent class I and II gingival recessions with modified coronally advanced tunnel and a new xenogeneic acellular dermal matrix. Journal of Esthetic and Restorative Dentistry. ,vol. 30, pp. 89- 95 ,(2018) , 10.1111/JERD.12337
Maurizio S. Tonetti, Pierpaolo Cortellini, Gaia Pellegrini, Michele Nieri, Daniele Bonaccini, Mario Allegri, Philippe Bouchard, Francesco Cairo, Gianpaolo Conforti, Ioannis Fourmousis, Filippo Graziani, Adrian Guerrero, Jan Halben, Jacques Malet, Giulio Rasperini, Heinz Topoll, Hannes Wachtel, Beat Wallkamm, Ion Zabalegui, Otto Zuhr, Xenogenic collagen matrix or autologous connective tissue graft as adjunct to coronally advanced flaps for coverage of multiple adjacent gingival recession: Randomized trial assessing non-inferiority in root coverage and superiority in oral health-related quality of life. Journal of Clinical Periodontology. ,vol. 45, pp. 78- 88 ,(2018) , 10.1111/JCPE.12834
Horacio Bach, Melissa Richard-Greenblatt, Eviatar Bach, Marcelo Chaffer, Wanika Lai, Greg Keefe, Douglas J. Begg, Protein Kinase G Induces an Immune Response in Cows Exposed to Mycobacterium avium Subsp. paratuberculosis. BioMed Research International. ,vol. 2018, pp. 1- 9 ,(2018) , 10.1155/2018/1450828