Trends by anatomic site in the incidence of cutaneous malignant melanoma in Canada, 1969-93.

摘要: Trends in melanoma incidence by anatomic site were examined Canada where ascertainment of cancer has been a high standard. The analysis included 41,239 malignant melanomas registered between 1969 and 1993 used an age, period cohort modeling approach. estimated annual increase was 4.8% for males 3.1% females but slowed appreciably the later years. lifetime risk appeared to have peaked with women born about 1934 men 1944. age-standardized rates now stabilized are expected plateau near future. largest relative increases occurred upper limbs followed trunk both sexes. Comparable generation effects observed intermittently exposed sites patterns trend differed women. This supports due sex- site-specific pattern sun exposure. evidence, first time, more favorable trends among post-World War II generations is thought reflect reduced exposure UV rays. may possibly be earliest signs impact primary prevention programs, particularly if radiation also acts as tumor promoter.