Synthesis of Pyrazolines Promoted by Amberlyst-15 Catalyst.

作者: B. Shivarama Holla , M. Mahalinga , Boja Poojary , Mithun Ashok , P. M. Akberali

DOI: 10.1002/CHIN.200623120

关键词: Organic chemistryHydrazineYield (chemistry)Amberlyst-15Aldol reactionHydrazine derivativesCondensationAromatic ketonesChemistryCatalysis

摘要: The condensation of a series aromatic ketones with aldehydes under aldol conditions affords 1-aryl-3-(substituted-phenyl/phenyl furanyl/thienyl)-2-propen-1-ones 1. resulting propenones undergo facile and clean cyclization hydrazine substituted derivatives to yield 3-aryl-5-(substitutedphenyl/phenylfuranyl/thienyl)-2-pyrazolines 2. This reaction is carried out in the presence Amberlyst-15 catalyst afford above pyrazolines 2 considerably good yield. All synthesized compounds have been characterized by spectral studies.

参考文章(1)
M. Mahalinga, B. Shivarama Holla, Boja Poojary, Mithun Ashok, P. M. Akberali, Synthesis of pyrazolines promoted by Amberlyst-15 catalyst Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry. ,vol. 45, pp. 568- 571 ,(2006)