Effects of PARP-1 inhibitor and ERK inhibitor on epithelial mesenchymal transitions of the ovarian cancer SKOV3 cells.
作者： Shan Su , Xueyan Lin , Ning Ding , Hong Zhang , Qinghua Zhang
DOI: 10.1016/J.PHAREP.2016.08.001
关键词: Poly ADP ribose polymerase 、 Chemistry 、 Western blot 、 Mesenchymal stem cell 、 Real-time polymerase chain reaction 、 Oncology 、 Cancer research 、 Vimentin 、 MAPK/ERK pathway 、 Gentamicin protection assay 、 Ovarian cancer 、 Internal medicine
摘要: … the PARP-1 inhibitor PJ34 can significantly suppress PARP-1 … In the present study, we will discuss the effects of the PARP-1 … as well in ovarian cancer cisplatin resistant cell line SKOV-3. …
springer.com
sci-hub.se 参考文章(24)
Teresa L. Andreone, Michael O’Connor, Alvin Denenberg, Paul W. Hake, Basilia Zingarelli, Poly(ADP-Ribose) Polymerase-1 Regulates Activation of Activator Protein-1 in Murine Fibroblasts The Journal of Immunology. ,vol. 170, pp. 2113- 2120 ,(2003) , 10.4049/JIMMUNOL.170.4.2113
Csaba Szabo, Pal Pacher, Raymond A. Swanson, Novel modulators of poly(ADP-ribose) polymerase Trends in Pharmacological Sciences. ,vol. 27, pp. 626- 630 ,(2006) , 10.1016/J.TIPS.2006.10.003
S J Veuger, J E Hunter, B W Durkacz, Ionizing radiation-induced NF-κB activation requires PARP-1 function to confer radioresistance Oncogene. ,vol. 28, pp. 832- 842 ,(2009) , 10.1038/ONC.2008.439
David Martín-Oliva, Francisco O'Valle, Jose A Muñoz-Gámez, M Teresa Valenzuela, M Isabel Nuñez, Mariano Aguilar, JM Ruiz de Almodóvar, Raimundo Garcia del Moral, F Javier Oliver, Crosstalk between PARP-1 and NF-kappaB modulates the promotion of skin neoplasia. Oncogene. ,vol. 23, pp. 5275- 5283 ,(2004) , 10.1038/SJ.ONC.1207696
Malka Cohen-Armon, Leonid Visochek, Dana Rozensal, Adi Kalal, Ilona Geistrikh, Rodika Klein, Sarit Bendetz-Nezer, Zhong Yao, Rony Seger, DNA-Independent PARP-1 Activation by Phosphorylated ERK2 Increases Elk1 Activity: A Link to Histone Acetylation Molecular Cell. ,vol. 25, pp. 297- 308 ,(2007) , 10.1016/J.MOLCEL.2006.12.012
T. M. Kauppinen, W. Y. Chan, S. W. Suh, A. K. Wiggins, E. J. Huang, R. A. Swanson, Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2 Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 7136- 7141 ,(2006) , 10.1073/PNAS.0508606103
Seunghee Yoon, Rony Seger, The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions Growth Factors Journal. ,vol. 24, pp. 21- 44 ,(2006) , 10.1080/02699050500284218
Rony Seger, Edwin G. Krebs, The MAPK signaling cascade. The FASEB Journal. ,vol. 9, pp. 726- 735 ,(1995) , 10.1096/FASEBJ.9.9.7601337
Maria Manuela Rosado, Elisabetta Bennici, Flavia Novelli, Claudio Pioli, Beyond DNA repair, the immunological role of PARP-1 and its siblings. Immunology. ,vol. 139, pp. 428- 437 ,(2013) , 10.1111/IMM.12099
Alexei Tulin, Allan Spradling, Chromatin Loosening by Poly(ADP)-Ribose Polymerase (PARP) at Drosophila Puff Loci Science. ,vol. 299, pp. 560- 562 ,(2003) , 10.1126/SCIENCE.1078764