Racial disparity in survival among patients with advanced/recurrent endometrial adenocarcinoma

摘要: BACKGROUND. Previous studies have reported shorter survival of black women compared with white who had advanced/recurrent endometrial cancer. It has been suggested that this may reflect racially based differences in treatment. METHODS. The authors retrospectively reviewed data from 169 and 982 International Federation Gynecologic Oncology (FIGO) Stage III, IV, or recurrent carcinoma were participants 1 4 Group randomized treatment trials doxorubicin alone combined paclitaxel and/or cisplatin. Demographic, histologic, treatment, outcome analyzed to estimate survival, between-group comparisons performed. RESULTS. The pooled revealed more likely papillary serous histology (P < .001), IV disease higher tumor grade .001) women, was worse among than (median 10.6 months vs. 12.2 months, respectively; P .001). A Cox proportional hazards regression analysis adjusted for performance status, stage, histology, grade, demonstrated (hazards ratio, 1.26, 95% confidence interval, 1.06–1.51; = .010). CONCLUSIONS. The a large group cancer racial disparity persists, despite the finding received similar treatment. Although causes remain be elucidated, socioeconomic, biologic, cultural factors should investigated identify etiologic origins multifactorial healthcare problem. Cancer 2006. Published 2006 by American Society