Effect of nontransmural necrosis on epicardial potential fields. Correlation with fiber direction.

作者: S Watabe , B Taccardi , R L Lux , P R Ershler

DOI: 10.1161/01.CIR.82.6.2115

关键词: ClockwiseQRS complexWall thicknessEndocardiumEpicardial pacingFiberMedicineElectrocardiographyAnatomyLeft ventricular wall

摘要: The effect of nontransmural necrosis on epicardial potential distributions was studied in 13 dogs. In previous studies, left ventricular pacing generated maps at QRS onset with a negative central area and two positive areas that faced the portions wavefront propagating along fibers. Subsequently, expanded counterclockwise direction by 90 degrees to 120 degrees. those rotatory expansion tentatively attributed spread excitation through deep myocardial layers, where fiber rotated from epicardium endocardium. To test this hypothesis, we tried interrupt creating localized, various depths wall injection formalin or application laser energy. Epicardial were obtained grid 12 x 15 electrodes 44 56-mm area. selected sites which some missing compared controls. straight line joining site positivity correlated well average necrotic mass (r = 0.82, p less than 0.01). Angle between described above depth necrosis, expressed as percent thickness 0.95, These data support hypothesis occurring after results spreading fibers.(ABSTRACT TRUNCATED AT 250 WORDS)

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