Pial synangiosis for moyamoya syndrome in children with sickle cell anemia: a comprehensive review of reported cases

作者: Benjamin C Kennedy , Michael M McDowell , Peter H Yang , Caroline M Wilson , Sida Li

DOI: 10.3171/2013.10.FOCUS13405

关键词: SurgerySignificant riskStrokeBrain ischemiaMoyamoya diseasePopulationPial synangiosisSickle cell anemiaMedicine

摘要: Object Pediatric patients with sickle cell anemia (SCA) carry a significant risk of developing moyamoya syndrome (MMS) and brain ischemia. The authors sought to review the safety efficacy pial synangiosis in treatment MMS children SCA by performing comprehensive all previously reported cases literature. Methods retrospectively reviewed clinical radiographic records 17 pediatric treated at Morgan Stanley Children's Hospital New York (MSCHONY) who developed radiological evidence underwent between 1996 2012. then added any additional for this population literature combined analysis outcomes. Results data consisted 48 procedures performed 30 patients. Of these, 27 (90%) presented seizure, stroke, or transient ischemic attack, whereas 3 (10%) were referre...

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