Influence of renal dysfunction on mortality after cardiac surgery: modifying effect of preoperative renal function.

作者: Charuhas V. Thakar , Sarah Worley , Susana Arrigain , Jean-Pierre Yared , Emil P. Paganini

DOI: 10.1111/J.1523-1755.2005.00177.X

关键词: Kidney diseaseRenal functionSurgeryNephrologyRisk of mortalityMortality rateCardiologyInternal medicineRisk factorDialysisCardiac surgeryMedicine

摘要: Influence of renal dysfunction on mortality after cardiac surgery: Modifying effect preoperative function. Background Acute failure (ARF) requiring dialysis is an independent risk factor surgery; the level function influences both postoperative ARF and mortality. The relationship between mild mortality, modifying baseline this association, less clear. Methods We studied 31,677 patients undergoing surgery 1993 2002. used a logistic regression model to assess while adjusting for function, dialysis, other factors. Results overall rate was 2.2% (698/31,677). For entire cohort, clinically relevant increase in adjusted occurred beyond 30% decline GFR. 5.9% ( N , 292/4986) among who developed or greater GFR not versus 0.4% 106/26,136) those with P Conclusion Renal surgery. A better attenuates mortality; interaction needs be considered defining threshold ARF.

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