作者: Peter Hollands
DOI: 10.1007/978-1-4471-4171-6_3
关键词: Cell biology 、 Blastocyst 、 Inner cell mass 、 Totipotent 、 Trophoblast 、 Embryo 、 Endoderm 、 Cell type 、 Ectoderm
摘要: When the first ever clinical embryologist, Bob Edwards, saw fertilization of a human oocyte in vitro he was witnessing not only momentous event medicine but also creation totipotent stem cells [249]. At point and up to early compaction, blastomeres embryo are generally considered be cells. These can differentiate into all cell types therefore have ability create complete new individual [60]. It is possible that enable correction developmental errors [87]. The data on come from experimental embryology using animal embryos as legal ethical restrictions experimentation restrict such work [84]. From this experimentation, it known develop endoderm, mesoderm ectoderm, germ cells, extraembryonic tissue, trophoblast. In mouse embryo, asymmetric divisions at eight-cell stage result two populations [111]. inner mass (ICM) blastocyst then develops positioned inside those outside trophectoderm which subsequently placenta [58, 72, 203]. Two ICM [76] are: