Interaction of Chlamydiae with Host Cells and Mucous Surfaces

摘要: For chlamydiae, as obligate intracellular parasites, attachment to and ingestion by host cells are essential steps in reproduction. Their site appears be heat-sensitive; it has not been correlated with any morphological entity. Antibody blocks chlamydial and, for certain chlamydia psittaci trachomatis strains which highly infective cell cultures, N-acetylglucosamine contribute receptor specificity. Sialic acid residues have suggested receptors other C. strains. The guinea-pig inclusion conjunctivitis strain of becomes associated the conjunctiva during incubation inoculated tissue fragments vitro. However, although antibody from tears neutralizes infectivity this vivo, association organism is inhibited, suggesting that neutralization vivo mediated prevention cells. Chlamydial monolayers greatly increased centrifugation. process temperature-dependent involves cooperative interactions between direction force pressure generated Enhanced result changes induced surface. These may favour nonspecific attachment, since inhibition on static overcome