Control of an amoebiasis outbreak in the Philippi area near Cape Town.

摘要: Previous studies in Durban have shown that serological investigations, combination with iso-enzyme electrophoresis, are invaluable for monitoring the endemicity of pathogenic strains Entamoeba histolytica. We therefore proposed antibody profiles could be used to detect epidemic situations. An outbreak amoebiasis normally non-endemic Philippi area near Cape Town provided an. opportunity testing this hypothesis. Seven 9 patients presenting at a district hospital invasive originated from single farm Philippi. Iso-enzyme electrophoresis and investigations were monitor endemici~of on 16 49 farms district. In an attempt contain disease transmission all inhabitants which came (including those where cyst-passers identified) seropositive subjects treated. The proved confirming hospitalised was central focus outbreak, also identified infected zymodemes E. histolytica adjacent 4 farms. On 5 these farms, 62,5 - 100% strongly positive. contrast weak negative responses occurred remaining 11 addition success treatment indicated by notable drop strong affected 11,5% within months. infection pathways implied strain introduced into foreigner endemic area; suggests pathogenicity is immutable stable feature.