作者: Heidi Lyng , Kolbein Sundfør , Gunnar Tanum , Einar K. Rofstad
DOI: 10.1007/978-1-4615-5399-1_9
关键词: Oncology 、 Limiting oxygen concentration 、 Internal medicine 、 Carcinoma 、 Lymph node 、 Oxygen 、 Pathology 、 Uterine cervix 、 Abnormal delivery 、 Oxygen tension 、 Extracellular 、 Medicine
摘要: Tumours often show low oxygen concentrations due to abnormal delivery and meta-bolism of (Vaupel et al., 1989; Gulledge Dewhirst, 1996). The vascular net-work is highly irregular with large intercapillary distances leading impaired blood supply. capacity the carry reduced because extracellular pH. Moreover, demand elevated high proliferation activity tu-mour cells. These characteristics lead development hypoxic necrotic areas within tumours. However, concentration can differ considerably among differ-ent tumours, even tumours same histological type.