Genetic diversity of community-associated methicillin-resistant Staphylococcus aureus in southern Stockholm, 2000-2005.
作者： H. Fang , G. Hedin , G. Li , C.E. Nord
DOI: 10.1111/J.1469-0691.2007.01941.X
关键词: Virology 、 Microbiology 、 Methicillin-resistant Staphylococcus aureus 、 Multilocus sequence typing 、 Staphylococcus aureus 、 Panton–Valentine leukocidin 、 Genotyping 、 Pulsed-field gel electrophoresis 、 Typing 、 Biology 、 Molecular epidemiology
摘要: This study investigated the molecular epidemiology of 104 community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) isolates from southern Stockholm during period 2000-2005. The were analysed by pulsed-field gel electrophoresis (PFGE), multilocus sequence typing, staphylococcal chromosomal cassette (SCC) mec typing and detection genes encoding Panton-Valentine leukocidin (PVL). Overall, 28 distinct PFGE patterns 13 types (STs) identified. ST80, ST8, ST88 ST150 major CA-MRSA clones in area, these accounted for 75% (78/104) all isolates. isolates, which have, to date, been found only Sweden, isolated exclusively a group homeless individuals. Eighty-six (83%) possessed SCCmecIV, ten different STs, while 16 SCCmecV. PVL detected 56% (58/104) Strain ST80-MRSA-IV carrying predominated over 6-year 38% However, polyclonal tendency was observed among recovered recent years.
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