Styrenic block copolymers for biomaterial and drug delivery applications.
作者： Shrirang V. Ranade , Robert E. Richard , Michael N. Helmus
DOI: 10.1016/J.ACTBIO.2004.09.004
关键词: Nanotechnology 、 Materials science 、 Biological property 、 Biocompatible material 、 Materials testing 、 Drug delivery 、 Organic chemistry 、 Copolymer 、 Biomaterial 、 The Renaissance
摘要: The use of styrenic block copolymers has undergone a renaissance as biomaterial and drug delivery matrix. early promise posed by the physical biological properties these for implantable medical devices was not met. However, there been an increased understanding role microphase separation on mediation response. Poly (styrene-b-isobutylene-b-styrene) (SIBS) copolymer critical enabling related to processing, vascular compatibility bio-stability that resulted in its matrix paclitaxel from Boston Scientific's TAXUS coronary stent. These will allow continuing development based SIBS meet demanding requirements.
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