Novel bedside techniques for functional residual capacity measurement

摘要: Functional residual capacity (FRC) is the gas volume remaining in lung following a normal expiration. The size of FRC may be compromised as result many pathophysiologic factors, including anesthesia, obesity, acute injury, and respiratory distress syndrome. Without sufficient volume, both blood oxygenation carbon dioxide excretion are limited, leading to hypoxemia, retention, possible morbidity mortality. Clinicians have long recognized potential for improved care from measurement availability, researchers been looking an effective means bedside assessment during mechanical ventilation decades. useful, example, guiding management improve exchange patients with reduced FRC. Traditional methods valuable researching disease progression monitoring ambulatory patients, but impractical at bedside. Recent research has proposed better utility through volume-based such nitrogen or oxygen wash-in/ washout help address need measurement. However, give lower precision spontaneous effort high airway pressure. Furthermore, these systems cannot used circle breathing which commonly found operating room. Thus, remains automated, accurate that can intensive