Cholesterol absorption: regulation of cholesterol synthesis and elimination and within-population variations of serum cholesterol levels.

作者: T A Miettinen , Y A Kesäniemi

DOI: 10.1093/AJCN/49.4.629

关键词: EndocrinologyMetabolismChemistryReverse cholesterol transportInternal medicineHigh cholesterolCholesterolObesityFeces analysisLipoproteinPopulation

摘要: Obesity and dietary plant sterols were negatively associated with fractional absorption of cholesterol in a random population 63 middle-aged men. Absorbed increased linearly the increase intake. The higher absolute lower rates biliary secretion, fecal elimination, synthesis. findings also revealed that high serum levels total, LDL, HDL was low synthesis elimination cholesterol. Thus, efficiency absorbed significantly regulate are important determinants within-population variation

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