作者: Donald A. Levin
DOI: 10.1086/282668
关键词: Directional selection 、 Genetics 、 Penetrance 、 Biology 、 Inbreeding 、 Phenotype 、 Gene exchange 、 Population 、 Repertoire
摘要: It is proposed that inbreeding, directional selection, and drift in small peripheral isolates could alter the genetic milieu to point where developmental feedback regulatory devices would be disrupted. The consequence of such may sporadic penetrance expressions hidden by canalization. These variants add phenotypic repertoire an isolate, incorporated then fixed. Should isolate succeed establishing a new adaptive mode barriers gene exchange, it give rise discrete population system with which depart radically from those parental species.