2′,2′-Difluorodeoxycytidine Metabolism and Mechanism of Action In Human Leukemia Cells
作者： William Plunkett , Varsha Gandi , Sherri Chubb , Billie Nowak , Volker Heinemann
DOI: 10.1080/07328318908054215
关键词: Mechanism of action 、 Chemistry 、 Toxicity 、 DNA synthesis 、 Biochemistry 、 Ribonucleotide reductase 、 Metabolism 、 Metabolite 、 Ribonucleotide 、 Nucleotide 、 Molecular biology
摘要: Abstract The toxicity of 2′,2′-difluorodeoxycytidine is due to the inhibition DNA synthesis by a nucleotide metabolite either direct process and/or ribonucleotide reductase.
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sci-hub.se 参考文章(1)
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