Role of mitochondrial membrane permeabilization in apoptosis and cancer.

作者: Jean-Claude Martinou , Dominic James , Judith Henry-Mowatt , Caroline Dive

DOI: 10.1038/SJ.ONC.1207534

关键词: Bcl-2 familyApoptosisIntermembrane spaceBiologyCaspaseCellCancer cellMitochondrionCell cycleCell biology

摘要: … Since the overwhelming majority of cell death signals engage the mitochondrial (intrinsic) pathway, this article will review the permeabilization of the outer mitochondrial membrane (…

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