Isolated systolic hypertension: data on a cohort of young subjects from a French working population (IHPAF).

作者: J-M Mallion , L Hamici , G Chatellier , T Lang , P F Plouin

DOI: 10.1038/SJ.JHH.1001506

关键词: Pulse pressurePopulation studyCohortIncidence (epidemiology)PediatricsPopulationHeart rateBlood pressureMean arterial pressureMedicineInternal medicine

摘要: Elderly patients with isolated systolic hypertension (ISH)—systolic blood pressure (SBP) ⩾140 mmHg and diastolic (DBP) <90 mmHg—have increased mortality morbidity. The aim was to study the incidence of ISH in a younger population between 15 60 years age, measure pulse (PP), mean arterial (MAP) heart rate (HR) these subjects. consisted 27 783 subjects, aged 15–60 years, untreated for (HT) from cohort employees formed HT French working (AIHFP). BP HR were measured validated, automatic device after 5, 6 7 min at rest. prevalence 6.9% men, 2.3% women. This over 5% young men 40–44 years; it negligible women, but 50–54 about 10% (ie same level as age): PP subjects (46.9 mmHg) significantly higher than normotensive group (NT—40.9 mmHg); comparable both (65.5 mmHg) older (66 mmHg); (63.1 mmHg) women (61.5 mmHg). NT (≈5 bpm) whom decreased age. is not (30% 25% women), high elevated PP, MAP values. These data should be taken into account ISH, are considered cardio-vascular risk factors.

参考文章(31)
Athanase Benetos, Michel Safar, Annie Rudnichi, Harold Smulyan, Jacques-Lucien Richard, Pierre Ducimetière, Louis Guize, Pulse Pressure A Predictor of Long-term Cardiovascular Mortality in a French Male Population Hypertension. ,vol. 30, pp. 1410- 1415 ,(1997) , 10.1161/01.HYP.30.6.1410
Christopher J O'donnell, Paul M Ridker, Robert J Glynn, Klaus Berger, Umed Ajani, JoAnn E Manson, Charles H Hennekens, None, Hypertension and Borderline Isolated Systolic Hypertension Increase Risks of Cardiovascular Disease and Mortality in Male Physicians Circulation. ,vol. 95, pp. 1132- 1137 ,(1997) , 10.1161/01.CIR.95.5.1132
Stanley S. Franklin, William Gustin, Nathan D. Wong, Martin G. Larson, Michael A. Weber, William B. Kannel, Daniel Levy, Hemodynamic Patterns of Age-Related Changes in Blood Pressure: The Framingham Heart Study Circulation. ,vol. 96, pp. 308- 315 ,(1997) , 10.1161/01.CIR.96.1.308
Steve Wing, Ronald E. Aubert, John P. Hansen, Curtis G. Hames, Cecil Slome, Herman A. Tyroler, Isolated systolic hypertension in Evans county--I. Prevalence and screening considerations. Journal of Chronic Diseases. ,vol. 35, pp. 735- 742 ,(1982) , 10.1016/0021-9681(82)90097-2
Michael F O'Rourke, Charalambos Vlachopoulos, Robert M Graham, Spurious systolic hypertension in youth Vascular Medicine. ,vol. 5, pp. 141- 145 ,(2000) , 10.1177/1358836X0000500303
Jan Staessen, Antoon Amery, Robert Fagard, Isolated systolic hypertension in the elderly. Journal of Hypertension. ,vol. 8, pp. 393- 405 ,(1990) , 10.1097/00004872-199005000-00001
Charalambos Vlachopoulos, Michael O’Rourke, Diastolic pressure, systolic pressure, or pulse pressure? Current Hypertension Reports. ,vol. 2, pp. 271- 279 ,(2000) , 10.1007/S11906-000-0010-6