Endogenous BDNF is required for myelination and regeneration of injured sciatic nerve in rodents.

作者: Jian-Yi Zhang , Xue-Gang Luo , Cory J. Xian , Zhong-Hao Liu , Xin-Fu Zhou

DOI: 10.1111/J.1460-9568.2000.01312.X

关键词: Wallerian degenerationNeurotrophic factorsPeripheral nerve injuryNeuroscienceBiologyCell biologyRegeneration (biology)Nerve guidance conduitSciatic nerveLow-affinity nerve growth factor receptorRemyelination

摘要: Following a peripheral nerve injury, brain‐derived neurotrophic factor (BDNF) and the p75 neurotrophin receptor are upregulated in Schwann cells of the Wallerian degenerating nerves…

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