Regression modeling of competing risk using R: an in depth guide for clinicians

作者: L Scrucca , A Santucci , F Aversa

DOI: 10.1038/BMT.2009.359

关键词: Risk analysisStatisticsCompeting risksMedicineStatistical softwareInstructions for useModel selectionRegressionProportional hazards modelRegression analysis

摘要: We describe how to conduct a regression analysis for competing risks data. The use of an add-on package the R statistical software is described, which allows estimation semiparametric proportional hazards model subdistribution risk as proposed by Fine and Gray. J Am Stat Assoc 1999; 94: 496-509.

参考文章(17)
Melvin L. Moeschberger, Kevin P. Tordoff, Nidhi Kochar, 10 A Review of Statistical Analyses for Competing Risks Handbook of Statistics. ,vol. 27, pp. 321- 341 ,(2007) , 10.1016/S0169-7161(07)27010-5
John P. Klein, Mei-Jie Zhang, 9 Survival Analysis Handbook of Statistics. ,vol. 27, pp. 281- 320 ,(2007) , 10.1016/S0169-7161(07)27009-9
Fred S. Guthery, Kenneth P. Burnham, David R. Anderson, Model Selection and Multimodel Inference: A Practical Information-Theoretic Approach The Journal of Wildlife Management. ,vol. 67, pp. 655- ,(2003) , 10.2307/3802723
Jason P. Fine, Robert J. Gray, A Proportional Hazards Model for the Subdistribution of a Competing Risk Journal of the American Statistical Association. ,vol. 94, pp. 496- 509 ,(1999) , 10.1080/01621459.1999.10474144
Brent R. Logan, Mei-Jie Zhang, John P. Klein, Regression Models for Hazard Rates Versus Cumulative Incidence Probabilities in Hematopoietic Cell Transplantation Data Biology of Blood and Marrow Transplantation. ,vol. 12, pp. 107- 112 ,(2006) , 10.1016/J.BBMT.2005.09.005
JP Klein, JD Rizzo, M-J Zhang, N Keiding, Statistical methods for the analysis and presentation of the results of bone marrow transplants. Part 2: Regression modeling. Bone Marrow Transplantation. ,vol. 28, pp. 1001- 1011 ,(2001) , 10.1038/SJ.BMT.1703271
Mary Lunn, Don McNeil, Applying Cox regression to competing risks Biometrics. ,vol. 51, pp. 524- 532 ,(1995) , 10.2307/2532940
H. Akaike, A new look at the statistical model identification IEEE Transactions on Automatic Control. ,vol. 19, pp. 716- 723 ,(1974) , 10.1109/TAC.1974.1100705