Studies on Leukemia: I. Uric Acid Excretion

摘要: 1. The urinary excretion of uric acid was studied in 17 normal subjects and 38 patients with leukemia. mean by the 6.5 mg./Kg. body weight /24 hrs. 14 acute lymphoblastic leukemia 30.3 hrs.; 13 myeloblastic leukemia, 13.0 mg.; 6 chronic lymphocytic 5.2 5 myelocytic 13.5 mg. 2. Following therapy cortisone, 6-mercaptopurine or Amethopterin, increased cases as leukocyte count declined. As approached levels, decreased. xanthine guanine paralleled acid. 3. In association administration an aromatic nitrogen mustard derivative to one patient Myleran there only a slight increase excretion.