A morphometric comparison of trabecular structure of human ilium between microcomputed tomography and conventional histomorphometry.
作者： T. Uchiyama , T. Tanizawa , H. Muramatsu , N. Endo , H. E. Takahashi
关键词: Bone biopsy 、 Materials science 、 Microcomputed tomography 、 Biomedical engineering 、 Imaging technique 、 Anatomy 、 Bone area 、 Perimeter 、 Trabecular bone 、 2d images 、 Bone volume
摘要: Recently, an imaging technique using microcomputed tomography (micro-CT) has emerged as a method for nondestructively assessing the microarchitecture of unprocessed surgical bone biopsy specimens. Using micro-CT, two-dimensional (2D) axial images were obtained from undecalcified transiliac biopsies which taken 15 patients with various metabolic diseases. Total area, and perimeter determined, volume (BV/TV), trabecular thickness (Tb.Th), number (Tb.N), separation (Tb.Sp) calculated semiautomatically instantaneously. To evaluate validity this useful tool, results compared those conventional histomorphometry. There significant correlations between two techniques all parameters, correlation coefficients ranging 0.759 (Tb.N, P < 0.005) to 0.949 (BV/TV, 0.0001). Different resolutions seem lead major differences in values measured by methods. These factors may explain why Tb.N Tb.Th estimated area is lower than that BV/TV. Our show micro-CT based on 2D tool quantifying
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