Transformation with DNA from 5-azacytidine-reactivated X chromosomes

作者： L. Venolia , S. M. Gartler , E. R. Wassman , P. Yen , T. Mohandas

关键词: Barr body 、 DNA 、 Gene 、 Molecular biology 、 In vitro recombination 、 X-inactivation 、 X chromosome 、 Biology 、 Thymidine kinase 、 XIST

摘要: It has been shown that 5-azacytidine (5-Aza-Cyd) can reactivate genes on the inactive human X chromosome. It is assumed that the 5-Aza-Cyd acts by causing demethylation of the …