Measuring Equilibrium Bicarbonate Concentrations Directly in Cellular Mitochondria and in Human Serum Using Europium/Terbium Emission Intensity Ratios

作者: David G Smith , Robert Pal , David Parker

DOI: 10.1002/CHEM.201201738

关键词: TerbiumChemistrySerum albuminPhosphateLuminescenceLigandInorganic chemistryBicarbonateEuropiumConfocal microscopy

摘要: … of bicarbonate concentration in serum and within cellular mitochondria. The bicarbonate ion … Knowledge of the concentration and distribution of HCO 3 − within cellular compartments is …

参考文章(34)
S. Aime, E. Gianolio, E. Terreno, G. B. Giovenzana, R. Pagliarin, M. Sisti, G. Palmisano, M. Botta, M. P. Lowe, D. Parker, Ternary Gd(III)L-HSA adducts: evidence for the replacement of inner-sphere water molecules by coordinating groups of the protein. Implications for the design of contrast agents for MRI. Journal of Biological Inorganic Chemistry. ,vol. 5, pp. 488- 497 ,(2000) , 10.1007/PL00021449
C T Flear, S W Roberts, S Hayes, J C Stoddart, A K Covington, pK1' and bicarbonate concentration in plasma. Clinical Chemistry. ,vol. 33, pp. 13- 20 ,(1987) , 10.1093/CLINCHEM/33.1.13
Yann Bretonnière, Martin J. Cann, David Parker, Rachel Slater, Ratiometric probes for hydrogencarbonate analysis in intracellular or extracellular environments using europium luminescence. Chemical Communications. pp. 1930- 1931 ,(2002) , 10.1039/B206286K
Andrew Beeby, Ian M. Clarkson, Rachel S. Dickins, Stephen Faulkner, David Parker, Louise Royle, Alvaro S. de Sousa, J. A. Gareth Williams, Mark Woods, Non-radiative deactivation of the excited states of europium, terbium and ytterbium complexes by proximate energy-matched OH, NH and CH oscillators: an improved luminescence method for establishing solution hydration states Journal of The Chemical Society-perkin Transactions 1. pp. 493- 504 ,(1999) , 10.1039/A808692C
M. Tresguerres, S. K. Parks, E. Salazar, L. R. Levin, G. G. Goss, J. Buck, Bicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasis. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 442- 447 ,(2010) , 10.1073/PNAS.0911790107
William N. Lipscomb, Norbert Sträter, Recent Advances in Zinc Enzymology Chemical Reviews. ,vol. 96, pp. 2375- 2434 ,(1996) , 10.1021/CR950042J
Elizabeth J New, David Parker, David G Smith, James W Walton, Development of responsive lanthanide probes for cellular applications. Current Opinion in Chemical Biology. ,vol. 14, pp. 238- 246 ,(2010) , 10.1016/J.CBPA.2009.10.003
Robert Pal, Andrew Beeby, David Parker, Analysis of citrate in low-volume seminal fluid samples using a time-gated measurement of europium luminescence Journal of Pharmaceutical and Biomedical Analysis. ,vol. 56, pp. 352- 358 ,(2011) , 10.1016/J.JPBA.2011.05.023
Yann Bretonniere, Martin J. Cann, David Parker, Rachel Slater, Design, synthesis and evaluation of ratiometric probes for hydrogencarbonate based on europium emission. Organic and Biomolecular Chemistry. ,vol. 2, pp. 1624- 1632 ,(2004) , 10.1039/B400734B
Joel D. Kopple, Kamyar Kalantar-Zadeh, Rajnish Mehrotra, Risks of chronic metabolic acidosis in patients with chronic kidney disease Kidney International. ,vol. 67, pp. S21- S27 ,(2005) , 10.1111/J.1523-1755.2005.09503.X