Privileged chiral ligands and catalysts

摘要: Preface BINAP Introduction: Structural Consideration Hydrogenation of Olefins Ketones Isomerization Allylamines and Allylalcohols Hydroboration, Hydrosilylation, Hydroacylation, Hydroamination Allylic Alkylation Heck Reaction Aldol Mannich-Type Reactions Nucleophilic Additions to Carbonyl Imino Compounds Alpha-Substitution Michael-Type Conjugate Using Organoboron Grignard Reagents Diels-Alder Ene Cyclization Ring-Opening Concluding Remarks BISPHOSPHACYCLES - FROM DuPHOS AND BPE TO A DIVERSE SET OF BROADLY APPLIED LIGANDS Introduction Development Bisphosphacycle Ligands Applications JOSIPHOS LIGANDS: DISCOVERY TECHNICAL APPLICATIONS Background Discovery the Josiphos Ligand Family Why Are So Effective? Catalytic Profile CHIRAL SPIRO Preparation Chiral Spiro Asymmetric Carbon-Carbon Bond Forming Carbon-Heteroatom Conclusion BISOXAZOLINE Enantioselective Formation Cycloaddition Conclusions PHOX Synthesis Substitution Decarboxylative Tsuji Allylations Cycloadditions Miscellaneous SALEN COMPLEXES Salen Complexes Properties Catalyzed by Outlook BINOL in Reduction Oxidation Metal/BINOL Lewis Acid Catalysts C-C Acid/Base Bifunctional Organocatalysis Summary TADDOLATE C=O Double Bonds Electron-Deficient C=C Substitutions CINCHONA ALKALOIDS Metal Catalysis Phase-Transfer Base Cooperative Multifunctional PROLINE DERIVATIVES Proline as Organocatalyst Analogs Organocatalysts 5-Pyrrolidin-2-yltetrazole Pyrrolidine-Based Sulfonamides Amides Pyrrolidine Diamine Diarylprolinols or Diarylprolinol Ether