Delivery of packaged rna to mammalian cells

作者: Stanislaw J. Kaczmarczyk , Deb K. Chatterjee

DOI:

关键词: RepliconCellRNAVirologyBiologyCytopathic effectAlphavirusPolynucleotideA protein

摘要: Described herein are compositions relating to alphavirus-based virus-like particles (VLPs) and methods for making using the described VLPs. The include VLPs vectors cells used produce Also included related VLPs, transduce a protein or polynucleotide of interest in target cell replicons that allow expression proteins polynucleotides without cytopathic effect.