Inhibition of PKR ameliorates lipopolysaccharide-induced acute lung injury by suppressing NF-κB pathway in mice
作者： Yinjiao Li , Jinglei Xiao , Yongchang Tan , Jun Wang , Yan Zhang
DOI: 10.1080/08923973.2017.1303839
关键词: Proinflammatory cytokine 、 Medicine 、 Inflammation 、 Immunology 、 TUNEL assay 、 NF-κB 、 Lung injury 、 Molecular biology 、 Protein kinase R 、 Tumor necrosis factor alpha 、 Kinase
摘要: … In the present study, we investigated the effects of PKR specific inhibition on LPS-induced lung inflammation and apoptosis and explored the role of PKR in NF-κB signaling. …
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