Differential performance on tasks of affective processing and decision-making in patients with Panic Disorder and Panic Disorder with comorbid Major Depressive Disorder.

摘要: Abstract Background Neuropsychological studies have provided evidence for deficits in psychiatric disorders, such as schizophrenia and mood disorders. However, neuropsychological function Panic Disorder (PD) or PD with a comorbid diagnosis of Major Depressive (MDD) has not been comprehensively studied. The present study investigated functioning patients + MDD by focusing on tasks that assess attention, psychomotor speed, executive function, decision-making, affective processing. Methods Twenty-two unmedicated PD, eleven whom had secondary MDD, were compared to twenty-two healthy controls, matched gender, age, intelligence memory, processing from the Cambridge Test Automated Battery (CANTAB), Gamble Task, Affective Go/No-go Task. Results Relative displayed an attentional bias toward negatively-valenced verbal stimuli (Affective Task) longer decision-making latencies (Cambridge Task). Furthermore, group committed more errors task memory visual discrimination their controls. In contrast, no differences found relative control subjects. Limitations sample size was limited, however, all drug-free at time testing. Conclusions demonstrated involving working towards stimuli. addition, depression qualitatively different responses areas processes.