Lanthanide-Labeled DNA
作者： Paul R. Selvin
关键词: Chemistry 、 Combinatorial chemistry 、 Autofluorescence 、 Förster resonance energy transfer 、 Lanthanide 、 DNA 、 Enhanced sensitivity 、 Energy transfer 、 Lanthanide probes
摘要: Lanthanides, as alternative probes to conventional fluorophores, can lead enhanced sensitivity in applications where autofluorescence is a problem. Multiple labeling with lanthanide chelates have been shown be an effective method for further increases sensitivity. These probes, being nonisotopic, avoid the many practical problems associated radioactive probes. Lanthanide are particularly advantageous resonance energy transfer, whether measuring distances biocomplexes or when used generate new lifetime tailored dyes.
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P. R. Selvin, Luminescent Lanthanide Chelates for Improved Resonance Energy Transfer and Application to Biology Springer Berlin Heidelberg. pp. 457- 487 ,(1999) , 10.1007/978-3-642-59903-3_19
Joseph R. Lakowicz, Long-Lifetime Metal—Ligand Complexes Springer, Boston, MA. pp. 573- 594 ,(1999) , 10.1007/978-1-4757-3061-6_20
Ewald Terpetschnig, Henryk Szmacinski, Joseph R. Lakowicz, Long-lifetime metal-ligand complexes as probes in biophysics and clinical chemistry. Methods in Enzymology. ,vol. 278, pp. 295- 321 ,(1997) , 10.1016/S0076-6879(97)78016-9
B. Alpha-Bazin, H. Bazin, M. Préaudat, E. Trinquet, G. Mathis, Rare Earth Cryptates and TRACE Technology as Tools for Probing Molecular Interactions in Biology New Trends in Fluorescence Spectroscopy. pp. 439- 455 ,(2001) , 10.1007/978-3-642-56853-4_21
Anders Bjartell, Sari Laine, Kim Pettersson, Elise Nilsson, Timo Lövgren, Hans Lilja, Time-resolved fluorescence in immunocytochemical detection of prostate-specific antigen in prostatic tissue sections. Histochemical Journal. ,vol. 31, pp. 45- 52 ,(1999) , 10.1023/A:1003504115690
S.-Y. Simon Chen, B. Wieb van der Meer, Ernest George Coker, Resonance Energy Transfer: Theory and Data ,(1994)
Brian Herman, X. F. Wang, Fluorescence imaging spectroscopy and microscopy J. Wiley. ,(1996)
Jean-Marie Lehn, JL Atwood, JED Davies, DD MacNicol, F Vögtle, Comprehensive Supramolecular Chemistry ,(1996)
Larry J. Kricka, Nonisotopic probing, blotting, and sequencing Academic Press. ,(1995)
Wolfgang Rettig, Bernd Strehmel, Sigurd Schrader, Holger Seifert, Applied Fluorescence in Chemistry, Biology and Medicine Springer Berlin Heidelberg. ,(1999) , 10.1007/978-3-642-59903-3