Influence of urinary sialic acid on calcium oxalate crystal formation.

作者: E. Konya , N. Amasaki , T. Umekawa , M. Iguchi , T. Kurita

DOI: 10.1159/000058451

关键词: Caox crystalSialic acidSeed crystalOsteopontinCalcium oxalateBiochemistryMedicineOxalateCrystallizationScanning electron microscope

摘要: Using seed crystal method, whole-urine and scanning electron microscopy, the inhibitory effects of sialic acid osteopontin (OPN) on aggregation/growth CaOx crystals were investigated. showed an effect in a concentration-dependent manner, but almost no was observed using method. OPN both experimental systems. The asialo-OPN approximately 20% lower than that experiment method 15% Scanning microscopy inhibit aggregation crystals. above findings show accounts for about 15-20% involvement crystallization.

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