Cell-specific Cre-mediated activation of the diphtheria toxin gene in pituitary tumor cells: potential for cytotoxic gene therapy.

作者: Eun Jig Lee , J. Larry Jameson

DOI: 10.1089/10430340252809829

关键词: Genetic enhancementDiphtheria toxinCre recombinaseSuicide geneGene expressionDiphtheriaMolecular biologyPituitary tumorsCytotoxic T cellBiology

摘要: Diphtheria toxin has been suggested for the treatment of malignant cancer. In this paper, we describe a strategy targeting expression diphtheria gene to growth hormone (GH)-pro...

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