Continued endothelial cell loss ten years after lens implantation.

摘要: Purpose: To investigate the effects of cataract extraction and lens implantation on central corneal endothelium 10 years after surgery. Methods: The authors conducted a prospective study 253 consecutive eyes that underwent with or without by one surgeon from 1976 to 1982. Three types implant were used during this period. protocol included ophthalmic examinations specular microscopy all preoperatively, 2 months 1, 3, 5, postoperatively. Results: 10-year analysis was 67 (26%) total eyes. remaining patients died (86 [34%]), unable return later (93 [37%]), had secondary implants (5 [2%]) penetrating keratoplasty (2 [1 %]). There no statistically significant differences among median 10year endothelial cell losses 36% in 17 control extractions (15 extracapsular intracapsular), 40% 15 medallion iris suture implants, 32% 28 transiridectomy clip 7 posterior chamber implants. exponential rate chronic loss 1 surgery 2.5% per year, which did not differ significantly three groups between (2.4% year) controls (2.7% year). higher (7.2% six cornea guttata, only preoperative morphologic feature associated rate. Conclusions: Ten extraction, continued lose cells at 2.5 8.0 times healthy unoperated affected presence used. Postoperative guttata more than twice Preoperative provide additional information helpful predicting postoperative status outcome.