作者: C Bonaiti , M L Briard , J Feingold , B Pavy , J Psaume
DOI: 10.1136/JMG.19.1.8
关键词: Incidence (epidemiology) 、 Medicine 、 Obstetrics 、 Allele frequency 、 Epidemiology 、 Pregnancy 、 Genetics 、 Maternal effect 、 Sex ratio 、 Abortion
摘要: The frequencies of cleft lip with or without palate (CL(P)) and isolated (CP) have been estimated in France to be 0.082% 0.035%, respectively, after exclusion malformation syndromes. A genetic epidemiological study has carried out on 468 patients CL(P) 163 CP. results are given detail some specific points discussed: the apparently low incidence France, relationship between sex ratio abortion rates, maternal effects, possibility an association