Inhibiting adenosine deaminase modulates the systemic inflammatory response syndrome in endotoxemia and sepsis
作者： Simon Adanin , Igor V. Yalovetskiy , Beth A. Nardulli , Albert D. Sam , Živojin S. Jonjev
DOI: 10.1152/AJPREGU.00373.2001
关键词: Endogeny 、 Proinflammatory cytokine 、 Adenosine receptor 、 Biology 、 Inflammation 、 Systemic inflammatory response syndrome 、 Immunology 、 Adenosine A3 receptor 、 Adenosine deaminase 、 Adenosine
摘要: By pharmacological manipulation of endogenous adenosine, using chemically distinct methods, we tested the hypothesis that adenosine tempers proinflammatory cytokine responses and oxyradi...
sci-hub.se 参考文章(39)
Fält K, Arvidsson S, Haglund U, Feline E. coli bacteremia--effects of misoprostol/scavengers or methylprednisolone on hemodynamic reactions and gastrointestinal mucosal injury. Acta chirurgica Scandinavica. ,vol. 156, pp. 215- 221 ,(1990)
C W Broner, G R Schonbaum, D Fairclough, D C Stokes, J L Shenep, J E Rehg, G L Stidham, W K Hildner, Effect of antioxidants in experimental Escherichia coli septicemia. Circulatory shock. ,vol. 29, pp. 77- 92 ,(1989)
R. Silverstein, D. C. Morrison, Wei-Wei Zhou, M. J. Parmely, D. R. Borcherding, C. K. Edwards, Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge. Journal of Immunology. ,vol. 151, pp. 389- 396 ,(1993)
Vladimir Kvetan, Zoltán H. Németh, Stephen McCarthy Pastores, Csaba Szabó, Csaba Szabó, E. Vízi, G. Haskó, Adenosine Receptor Agonists Differentially Regulate IL-10, TNF-α, and Nitric Oxide Production in RAW 264.7 Macrophages and in Endotoxemic Mice Journal of Immunology. ,vol. 157, pp. 4634- 4640 ,(1996)
A Marchant, P Stordeur, O Le Moine, M Goldman, L Schandené, D de Groote, J Devière, Adenosine enhances IL-10 secretion by human monocytes. Journal of Immunology. ,vol. 156, pp. 4408- 4414 ,(1996)
R Hirschhorn, M Philips, B N Cronstein, S B Abramson, G Weissmann, R I Levin, Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. Journal of Immunology. ,vol. 148, pp. 2201- 2206 ,(1992)
J Haynes, W J Thompson, P D Peterson, D W Killilea, Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic-3',5'-guanosine monophosphate-stimulated phosphodiesterase to reverse hypoxic pulmonary vasoconstriction in the perfused rat lung. Journal of Pharmacology and Experimental Therapeutics. ,vol. 276, pp. 752- 757 ,(1996)
K Takabayashi, G S Firestein, F G Sajjadi, R C Domingo, A C Foster, Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors. Journal of Immunology. ,vol. 156, pp. 3435- 3442 ,(1996)
K M Mullane, B Sambol, A Montag, G S Firestein, D A Bullough, D Boyle, F G Sajjadi, H E Gruber, Protective effect of an adenosine kinase inhibitor in septic shock. Journal of Immunology. ,vol. 152, pp. 5853- 5859 ,(1994)
KUNIHIKO ITOH, TOSHIRO MAJIMA, KIYOTO EDO, MICHINAO MIZUGAKI, NAKAO ISHIDA, Suppressive effect of 1-methyladenosine on the generation of chemiluminescence by mouse peritoneal macrophages stimulated with opsonized zymosan. Tohoku Journal of Experimental Medicine. ,vol. 157, pp. 205- 214 ,(1989) , 10.1620/TJEM.157.205