VACCINE SAFETY: REAL AND PERCEIVED ISSUES

作者: NEALA. HALSEY

DOI: 10.1016/B978-012107258-2/50028-7

关键词: DiseaseMedicinePremature deathNeurological DamageVaccine safetyMedical emergencyVery low riskBlindnessIntensive care medicineAdverse effectHealth care

摘要: Most adverse events caused by the vaccines are mild, and serious usually rare. Vaccines most effective tools available for prevention, control of infectious diseases. Widespread use has prevented millions premature deaths, paralysis, blindness, neurological damage. When compared to risk complications from diseases that protect against, risks consequences 1000-fold, or greater with natural disease than vaccine. Vaccines, which administered healthy people, held a higher safety standard medications treat people who already ill. often given universally infants children as even very low side effects can result in substantial population-attributable risk. Efforts need be made increase understanding general public, healthcare practitioners how vaccine issues properly investigated, what constitutes evidence causal relationships order minimize public used against disease, safe possible.

参考文章(67)
S. Ghosh, Li Jin, Measles virus persistence in specimens of inflammatory bowel disease and autism cases. Digestive Diseases and Sciences. ,vol. 46, pp. 658- 660 ,(2001) , 10.1023/A:1005632106643
Arthur R. Ablin, Thomas K. Walter, Michael M. Siegel, Measles pneumonia in childhood leukemia. Pediatrics. ,vol. 60, pp. 38- 40 ,(1977)
Maria A. Deloria, Mark C. Steinhoff, Margaret B. Rennels, Michael D. Decker, Edwin L. Anderson, Bruce D. Meade, Kathryn M. Edwards, Michael E. Pichichero, Janet A. Englund, George F. Reed, A randomized comparison of reactogenicity and immunogenicity of two whole-cell pertussis vaccines. Pediatrics. ,vol. 96, pp. 567- 570 ,(1995)
G. J. Bhat, V. K. Diwan, C. Chintu, M. Kabika, J. Masona, HIV, BCG and TB in Children: A Case Control Study in Lusaka, Zambia Journal of Tropical Pediatrics. ,vol. 39, pp. 219- 223 ,(1993) , 10.1093/TROPEJ/39.4.219
A. Tourbah, O. Gout, R. Liblau, O. Lyon-Caen, C. Bougniot, M. T. Iba-Zizen, E. A. Cabanis, Encephalitis after hepatitis B vaccination: recurrent disseminated encephalitis or MS? Neurology. ,vol. 53, pp. 396- 396 ,(1999) , 10.1212/WNL.53.2.396
Roger H. Bernier, Abscesses Complicating DTP Vaccination Archives of Pediatrics & Adolescent Medicine. ,vol. 135, pp. 826- 828 ,(1981) , 10.1001/ARCHPEDI.1981.02130330036011
P. M. Strebel, R. W. Sutter, S. L. Cochi, R. J. Biellik, E. W. Brink, O. M. Kew, M. A. Pallansch, W. A. Orenstein, A. R. Hinman, Epidemiology of Poliomyelitis in the United States One Decade after the Last Reported Case of Indigenous Wild Virus-Associated Disease Clinical Infectious Diseases. ,vol. 14, pp. 568- 579 ,(1992) , 10.1093/CLINIDS/14.2.568
CHRISTOPHER M. MARTIN, Controlled Trial of Live Measles Vaccine American Journal of Diseases of Children. ,vol. 106, pp. 267- 279 ,(1963) , 10.1001/ARCHPEDI.1963.02080050269004
Robert G. Sharrar, Philip LaRussa, Susan A. Galea, Sharon P. Steinberg, Ann R. Sweet, R.Michael Keatley, Matthew E. Wells, Wendy P. Stephenson, Anne A. Gershon, The postmarketing safety profile of varicella vaccine. Vaccine. ,vol. 19, pp. 916- 923 ,(2000) , 10.1016/S0264-410X(00)00297-8